Madagascar edges toward famine, UN food agency appeals for assistance
Madagascar edges toward famine, UN food agency appeals for assistance

And with acute malnutrition rates continuing to rise, urgent action is required to address this unfolding humanitarian crisis, the World Food Programme (WFP) warned. 

“If we don’t reverse this crisis, if we don’t get food to the people in the south of Madagascar, families will starve and lives will be lost”, Amer Daoudi, WFP’s Senior Director of Operations, said, after visiting one of the worst affected areas, Sihanamaro. 

Evolving catastrophe 

Most districts in the South are in the throes of a nutrition emergency with Global Acute Malnutrition (GAM) levels in children under five, nearly doubling over the last four months – touching an alarming 16.5 per cent – the Ministry of Health reported.  

Children with acute malnutrition are four times more likely to die than healthy youngsters. 

And in the worst affected district of Ambovombe, GAM has risen above 27 per cent, putting the lives of many children at risk.  

Meeting needs, saving lives 

Over the next six months, WFP needs $74 million to save lives in the world’s second-largest island State.  

“We have witnessed heart-breaking scenes of severely malnourished children and starving families”, said Mr. Daoudi, appealing for “money and resources…to help the people of Madagascar”. 

After the alarm was raised across Amboasary district, the UN agency has been progressively assisting up to 750,000 people through food and cash distributions each month. 

State of peril 

Consecutive years of drought in the South have left at least 1.35 million people in need of emergency food and nutrition assistance, according to WFP.  

Since last September, the start of the lean season, the situation had turned critical as families had already depleted their food supplies and gone through vital seed stocks, leaving nothing for the November/December 2020 planting season.  

Currently, up to 80 per cent of the population in certain areas in the south are resorting to desperate survival measures, such as eating locusts, raw red cactus fruits or wild leaves. 

Moreover, with a lack of rain during the last planting season, prospects for the 2021 harvest are poor, indicating another longer tougher lean season from October to March 2022.  

WFP said that food production this year is expected to be “less than 40 per cent of the last five-year average”, which only adds to the difficulties faced by communities already on the brink of survival to feed themselves. 

At the same time, semi-arid conditions in southern Madagascar, combined with high levels of soil erosion, deforestation and unprecedented sandstorms, have transformed arable land into wasteland across the region.

Increased cancer risk for petroleum industry workers and people living near plants: New UN study
Increased cancer risk for petroleum industry workers and people living near plants: New UN study

The findings add to increasing evidence of the health consequences of air pollution from petroleum extraction and refining.

Types of cancer risk

The review identified an increased risk of mesothelioma, skin melanoma, multiple myeloma, and cancers of the prostate and urinary bladder, and conversely, decreased risk of cancers of the oesophagus, stomach, colon, rectum, and pancreas.

Offshore petroleum work was associated with an increased risk of lung cancer and leukaemia.

Living close to petroleum facilities was also associated with an increased risk of childhood leukaemia.

Scientists in the Environment and Lifestyle Epidemiology Branch of the agency carried out 41 cohort studies, 14 case–control studies, and two cross-sectional studies to compile their review.

Their findings have been published in the International Journal of Environmental Research and Public Health.

More research needed

The authors point out that further studies on the effect of exposure to petroleum and its closest derivatives (e.g. benzene) are needed in order to identify how they modify cancer risk.

In particular, there is a need for targeted studies in under-researched areas of high petroleum production with presumably higher exposures.

The scientists argue that the best way forward may be an international consortium to guide new studies in Africa, the Middle East, and Asia, in order to harmonize how studies are carried out and how exposure is assessed.

UN providing equipment and supplies to help India fight rapid COVID-19 surge
UN providing equipment and supplies to help India fight rapid COVID-19 surge

“In India’s time of need, the UN is doing everything it can to rapidly provide critical equipment and supplies to central and state governments”, said Resident Coordinator Renata Lok Dessallien. 

WHO and sister agency the UN Children’s Fund, UNICEF, are procuring equipment and supplies, including 7,000 oxygen concentrators and 500 nasal devices for oxygen supply, in addition to oxygen generating plants, COVID-19 testing machines, and personal protective kits. 

“The current rapid surge of COVID-19 cases has put immense pressure on the health systems, already overburdened since the start of the pandemic. We need to act with speed, expand hospital capacities and equip them with medical supplies, most needed to save lives”, said Dr Poonam Khetrapal Singh, Regional Director for WHO in South-East Asia. 

The region has led the world in COVID-19 infections for a third straight week, mainly due to the situation in India, which has recorded 2.17 million new cases, or a 52 per cent increase. 

Mobile field hospitals 

WHO is helping India to scale-up additional hospital beds by procuring mobile field hospitals which could be set up in the most affected areas.  The field hospitals have a capacity of 20 to 30 beds but can be increased to a maximum of 50, if needed. 

The agency is also providing for laboratories to meet the huge demand for testing, and over 2,600 staff have been redeployed from programmes for polio and neglected tropical diseases to support pandemic response. 

Meanwhile, in the western state of Maharashtra, the second most populous in the country, UNICEF has engaged experts to work on risk governance.  

In it together 

India this week completed a 100-day COVID-19 vaccination drive, with 145 million doses administered. Dr Khetrapal Singh said efforts to ramp up vaccination coverage are needed. 

She also stressed the need to continue key public health measures, such as testing and contact tracing, along with physical distancing, proper hand washing and use of masks, to curtail virus transmission. 

Dr Khetrapal Singh underlined WHO’s commitment to continue working with health authorities at all levels, saying “Together we must do all we can to halt the current COVID-19 surge”.

COVID-19 cases rise for ninth consecutive week, variants continue spreading 
COVID-19 cases rise for ninth consecutive week, variants continue spreading 

Nearly 5.7 million new cases were reported in the last seven-day period, above previous highs, the World Health Organization (WHO) said in its latest coronavirus update published late Tuesday. 

The number of deaths from the virus also increased – now for the sixth consecutive week – with more than 87,000 confirmed victims. 

Southeast Asia spike 

All parts of the world reported falling numbers of infections, apart from Southeast Asia and Western Pacific regions. 

And although Southeast Asia reported the highest increases in infections and deaths for the third week in a row, it was India that accounted for the vast majority of cases, with 2.17 million new cases – a 52 per cent increase. 

This is the equivalent of nearly four in 10 global cases reported in the past week, followed by the United States (with 406,001 new cases, representing a 15 per cent decrease), Brazil (404,623 new cases, a 12 per cent decrease), Turkey (378,771 cases, a nine per cent decrease) and France (211,674 new cases, a nine per cent decrease). 

Mutations 

On the three known coronavirus variants of concern, WHO said that the so-called UK strain has been detected and verified in three more countries since last week, bringing the total to 139; that’s effectively most of the world, except Greenland and several central and southern African nations. 

The South African origin variant is in 87 countries and the mutations first found in Brazil and Japan, has been reported in 54. 

Monitoring is ongoing into seven other so-called “variants of interest”, the UN health agency said. 

Globally, there have been more than 148 million confirmed cases of COVID-19, including 3.1 million deaths, according to WHO.  

As of 27 April 2021, a total of 961,231,417 vaccine doses have been administered. 

WHO

COVID-19 cases and global deaths.

Risky business: COVID-19 and safety at work
Risky business: COVID-19 and safety at work

The world of work has been upended by COVID-19, and the effects are likely to be long-lasting. Before the pandemic, there were some 260 million home-based workers (not including domestic or care workers). The International Labour Organisation (ILO) estimates that figure could have doubled, with as many as one in three workers remote working in North America and Europe, and one in six in sub-Saharan Africa.

The rollout of vaccines, mainly in the developed world,  has increased the possibilities of a return to the workplace, but many companies and workers have signalled a wish to retain a degree of home working, after seeing some of the benefits. For employers, these include minimising the risk of contagion and  potentially spending less on expensive office space whilst staff no longer have to spend commuting to and from the workplace.

‘If you’re losing your mind, I’m right there with you’

However, whilst some are enjoying baking bread or taking a stroll during a conference call, and using the commuting time to indulge in new pursuits, others have been craving a return to a more structured work-life routine.

“I tell myself daily that I am grateful to have a job with understanding supervisors and colleagues. But all of it is hard. If you’re also a working mum losing her mind daily, know that I’m right there with you,” says Paulina, a New York-based teleworker.

“I have chaired meetings with a laptop and headphones on one side of a tiny, New York City kitchen while cooking lunch and having a screaming toddler wrapped around my ankles. While all of this is cute once or maybe twice, regular screams of children in the background can only be tolerated for so long. I should know, because I passed that line sometime in July.”

Stories such as this explain why a recent study by the International Labour Organisation (ILO) found that 41 per cent of people who worked from home considered themselves highly stressed, compared to 25 per cent of those who worked on-site.

“The most effective way to eliminate the risk of contagion in a work context is, for those who can do it, teleworking, says Joaquim Nunes, head of occupational health and safety at the ILO, “But we still need to pay attention to the physical and mental well-being of workers”.

As teleworking is likely to remain an important factor in many people’s jobs, Mr. Nunes says that work-related policies will have to be updated to reflect the new reality.

“There’s a good chance that the rise of teleworking during the COVID-19 pandemic will permanently change how we live and work. Many governments have realised this, and are taking a fresh look at the rights of employees working from home. For example, companies should ensure that workers do not feel isolated, whilst giving them the right to disconnect, rather than being online 24 hours a day”.

In Chile, a law adopted early in March 2020 goes some way to addressing some of these concerns. The legislation recognizes the right of remote workers to disconnect for at least 12 continuous hours in a 24-hour period. In addition, employers cannot require workers to respond to communications on rest days or holidays.

World Bank/Henitsoa Rafalia

A father takes care of his young child while working from home in Madagascar.

A healthy home?

Beyond the question of comfort and mental health, is one of physical safety. It is often said that most accidents happen at home, so, if this is where much of the working week is spent, should employers be responsible for making sure apartments aren’t death traps?

“For now, there are no easy answers when it comes to ensuring a suitable home office environment”, says Mr. Nunes. “However, we can say that the same principles that apply to other workplaces apply to teleworkers, in that employers have a general duty of care, as reasonably practicable. Employers can’t control the workplace when staff are working from home, but they can provide ergonomic equipment to workers, such as suitable chairs, and help them to assess their own risks and to learn about how to maintain healthy lifestyles.”

Teleworking is also challenging for enforcement agencies, as usually inspectors do not have free access to the private spaces. One solution to ensure compliance with legislation could be virtual inspections, which are already taking place in Nordic countries on a voluntary basis. “These involve labour inspectors video calling a worker at home, and being shown their work chair, desk, and lighting setup”, explains Mr. Nunes. “These inspections can serve as a way to monitor the home workplace and provide advice, but also raise understandable privacy concerns”.

ILO/Minette Rimando

A convenience store requires staff to wear a mask, observe physical distance, and use a plastic sheet barrier as safety measures to prevent the spread of COVID-19, Muntinlupa City, Philippines.

Frontline fears

Whilst the new teleworkers and their employers grappled with their new reality, a large part of the global workforce had no choice but to go to a physical place of work. The difficulties faced by health care workers were widely reported, but employees in several other industries had to brave the trip to the workplace – sometimes on crowded trains and buses – and, often, interact with other people, at considerable risk to their health.

In the US, these fears led to collective action by workers at Whole Foods, a grocery subsidiary of Amazon. On March 31, 2020, in response to seeing their colleagues testing positive with COVID-19, workers decided to call in sick, and demand sick leave, free coronavirus testing and hazard pay. This was followed in April by work stoppages at some of America’s biggest companies, including Walmart, Target and FedEx.

Whilst early advice on protection and prevention focused on measures such as hand washing, the wearing of masks and gloves, and physical distancing, the ILO quickly realised that more needed to be done to address work-related issues.

ILO/Yacine Imadalou

Vendors in a bakery in Constantine, Algeria, during the COVID-19 crisis.

“In the workplace, you have to think about more than just the individual worker: the whole environment needs to be protected’, explains Mr. Nunes. “One example that many of us will have come across is in shops and supermarkets, where it is now common to see PVC separators between cashiers and customers. Work surfaces are also being cleaned much more frequently, but this raises other concerns that need to be addressed, such as the potential for skin complaints or respiratory problems caused by the chemicals in cleaning products.”

Whilst areas such as healthcare and retail have been grappling with these issues for several months, other parts of the economy could soon be opening up. In several countries, plans are being made to allow gatherings of large numbers of people to take place, in venues such as concert halls and cinemas, and, heading into summer in the northern hemisphere, the range of permitted tourist activities looks set to expand.

However, for this to take place, and for economies to safely open, governments and employers, in collaboration with workers, will need to make sure that workers in these, and all other industries, are safe at their workplaces, and confident they will not be exposed to unnecessary risks, particularly those related to COVID-19.


Key workers need greater protections amidst COVID fight, new ILO report warns
Key workers need greater protections amidst COVID fight, new ILO report warns

A new report by the ILO, released to mark World Day for Safety and Health at Work, found that 7,000 health workers have died since the outbreak of the crisis, while 136 million health and social care workers are at risk of contracting COVID-19 through work.

The document, Anticipate, prepare and respond to crises. Invest now in resilient OSH (Occupation Safety and Health) systems, looks at how countries can minimize the risks for everyone in the workplace, in the event of future health emergencies.

It also highlights the mental health pressures associated with the pandemic: one in five healthcare workers globally, has reported depression and anxiety symptoms.

Strong, resilient safety systems

The report outlines the critical roles played during the pandemic by strong workplace guidance backed by enforcement, and calls for them to be dovetailed with national crisis emergency plans.

“There could be no clearer demonstration of the importance of a strong, resilient, occupational safety and health environment. Recovery and prevention will require better national policies, institutional and regulatory frameworks, properly integrated into crisis response frameworks”, said ILO Director-General Guy Ryder.

Pros and cons of teleworking

It’s not only health and care sectors that have proven to be sources of COVID-19 outbreaks.

Many workplaces where staff are in closed environments or spend time in close proximity with each other – including in shared accommodation or transport – are affected.

And while teleworking has been essential in limiting the spread of the virus, it has also blurred the lines between work and private life, adding to people’s mental stress.

Sixty-five per cent of enterprises surveyed by the ILO and the G20 OSH Network, focused on occupational safety, reported that worker morale has been difficult to sustain while teleworking.

The report stated that small and micro-sized enterprises have often found it hard to meet official safety-at-work requirements because many have lacked the resources to adapt to the threats posed by the pandemic.

In the informal economy, the UN agency warned that many of the world’s 1.6 billion workers in the sector, especially in developing countries, have continued working despite lockdowns, restrictions on movement and social interaction.

This has put them at high risk of catching the virus, yet most do not have access to basic social protection, such as sick leave or sick pay.

Social dialogue is key

International labour standards (ILS) offer specific guidance on how to respond to these challenges and reduce the risk of virus transmission in the workplace, the report says.

They provide tools to implement safety-first measures and to ensure that workers, employers and Governments, can maintain decent work, while adjusting to the socio-economic consequences of the pandemic.

ILS also encourage social dialogue as the best way to ensure that procedures and protocols are effectively implemented and accepted, the report concludes.


MEPs hold final debate on future EU-UK relations before signing off agreement | News | European Parliament
MEPs hold final debate on future EU-UK relations before signing off agreement

News | European Parliament

In a debate on Tuesday, Parliament’s political groups argued in favour of the agreement that sets the rules of the future EU-UK relationship.

Most MEPs as well as Commission President Ursula von der Leyen and the Portuguese Council Presidency stressed they regret the UK’s departure but argued for voting in favour of the Trade and Cooperation Agreement between the EU and the UK. It is the best option to cushion against the worst effects of Brexit and to ensure the integrity of the Single Market, they added.


Referring to unilateral UK measures in breach of the Withdrawal Agreement and its protocol on Northern Ireland, most speakers argued that the agreement will provide additional legal tools to prevent and protect against unilateral divergence from the obligations to which both parties signed up.

After four months of intense scrutiny, MEPs also underlined that Parliament will continue to play an active role in closely monitoring that the UK fully carries out its obligations.


Later today, Parliament will vote on whether to give its consent to the agreement and on a resolution setting out its evaluation of and expectations from the deal. Results are announced on Wednesday 28 April at 9am.

Watch the recording of the debate here and the press conference following the debate here.


Background

On 24 December 2020, EU and UK negotiators agreed on the Trade and Cooperation Agreement establishing the terms for future EU-UK cooperation. To minimise disruption, the agreement has been provisionally applied since 1 January 2021. Parliament’s consent is necessary for the agreement to enter into force permanently before it lapses on 30 April 2021.

‘Disasters know no borders’ says Guterres, 35 years on from Chernobyl nuclear accident
‘Disasters know no borders’ says Guterres, 35 years on from Chernobyl nuclear accident

A 20-second shut down of the Chernobyl nuclear power plant on 26 April 1986, created a surge that led to a chemical explosion, which released nearly 520 dangerous radionuclides into the atmosphere. As a result, large parts of the former Soviet Union were contaminated; territory which now lies within the borders of Belarus, Ukraine and Russia, according to the UN. 

Marking the 35th anniversary of the accident, Secretary-General António Guterres said that together, “we can work to prevent and contain [disasters]… support all those in need, and build a strong recovery”. 

Never forget 

As one of the most serious nuclear accidents in history, nearly 8.4 million people in the three countries were exposed to radiation, according to the UN. 

Some 350,000 were forced to leave their homes in severely contaminated areas, which left a deeply traumatic and lasting impact on their lives: “Their suffering must not be forgotten”, said the top UN official. 

He also pointed to the anniversary as an occasion to recognize the recovery efforts led by the three governments as well as the work of “scientists who sifted through the evidence” to provide important analysis that has informed emergency planning and reduced risks. 

A legacy of assistance 

While the Organization had helped the people in the areas surrounding Chernobyl at the onset, four years after the accident the Soviet Government acknowledged the need for international assistance.  

That same year, 1990, the General Assembly adopted a resolution calling for “international cooperation to address and mitigate the consequences at the Chernobyl nuclear power plant”. This began the UN’s participation in the recovery effort. 

In 2002, the world body announced a shift in the Chernobyl strategy, with a new focus on a long-term developmental approach. 

And in 2019, a new safety casing over the old shelter was completed and given to the Government of Ukraine. It was achieved with €2.2 billion in donations from over 45 nations.  

The UN said the milestone one of the largest ever seen projects in terms of international cooperation in the field of nuclear safety. 

Working for ‘the common good’ 

UN country teams – working with civil society, international partners and donors – first supported emergency and humanitarian aid, then recovery and finally social and economic development, Mr. Guterres noted, adding that “our joint efforts have enjoyed some success”. 

He cited that the number of small and medium-sized businesses operating in areas directly affected by the disaster has risen from 2,000 in 2002 to 37,000 today.  

And thousands of residents, community leaders and doctors have been trained on health risks and promoting healthy lifestyles. 

The Chernobyl disaster was contained by governments working with academics, civil society and others, “for the common good”, the UN chief said.  

“It holds important lessons for today’s efforts to respond to the COVID-19 pandemic”, he concluded.

National Chernobyl Museum/Anatoliy Rasskazov

The accident at the Chernobyl nuclear power plant on 26 April 1986 was one of the most serious nuclear accidents ever.

A ‘malaria-free future’ is possible, UN chief says on international day
A ‘malaria-free future’ is possible, UN chief says on international day

“We commend all countries that have reached the ambitious target of zero malaria”, said Secretary-General António Guterres.  

“Together, they are showing the world that a malaria-free future is possible”. 

‘Key to success’ 

Countries with zero malaria have reached the people at risk with the necessary services, from prevention to detection and treatment, regardless of citizenship or financial status,  said the top UN official.   

“Sustained funding, surveillance systems and community engagement have been the key to success”, he added.  

Yet, while these achievements deserve celebrating, it is important to remember the millions around the world who continue to suffer and die from this deadly illness.   

Each year, malaria claims the lives of more than 400,000 people, mainly young children in Africa.  And, every year, there are more than 200 million new cases of this fatal parasitic disease.   

With robust political commitment, adequate investment and the right mix of strategies, “malaria can be defeated”, upheld the UN Secretary-General.   

Stamping out malaria 

Between 2000 and 2019, the number of countries with fewer than 100 indigenous malaria cases increased from six to 27, according to the World Health Organization (WHO), calling it “a strong indicator” that malaria elimination is within reach.

The UN health agency lauded those countries that have already done so saying: “They provide inspiration for all nations that are working to stamp out this deadly disease and improve the health and livelihoods of their populations”.

Country breakdown 

In 2019, Africa shouldered 94 per cent of all malaria cases and deaths worldwide, with more than half of all cases occurring in the five countries of Nigeria, 27 per cent; Democratic Republic of the Congo, 12 per cent; Uganda and Niger, five per cent each; and Mozambique, four per cent, according to WHO.

During that same period, about three per cent per cent of malaria cases were reported in South-East Asia and two per cent in the Eastern Mediterranean region.  

The Americas and Western Pacific region each accounted for fewer than one per cent of all cases. 

Certifying zero malaria 

Certification of malaria elimination is WHO’s official recognition of a country’s malaria-free status, which it grants when a State has proven, beyond reasonable doubt, that the chain of indigenous malaria transmission has been interrupted nationwide for at least the past three consecutive years. 

Following 50 years of solid commitment by the Government and people of El Salvador to end the disease, in February it became the first country in Central America to receive the distinction. 

Meanwhile China, which  registered zero indigenous cases in 2016 and has stayed malaria-free to date, applied last year for the WHO malaria-free certification. 

Japan: UN experts ‘deeply disappointed’ by decision to discharge Fukushima water
Japan: UN experts ‘deeply disappointed’ by decision to discharge Fukushima water

“The release of one million tonnes of contaminated water into the marine environment imposes considerable risks to the full enjoyment of human rights of concerned populations in and beyond the borders of Japan”, said Marcos Orellana, Special Rapporteur on toxics and human rights, Michael Fakhri,  Special Rapporteur on Right to Food, and David Boyd, Special Rapporteur on human rights and the environment in a joint statement

‘Very concerning’ 

Given the warnings from environmentalists and some governments that the discharge would affect many people as well as the environment at large, the experts called the Government’s decision “very concerning”.  

It comes after years of discussions with communities – including the fishing sector, which was already severely hit by the 2011 disaster – environmental NGOs, neighbouring countries and civil society.  

“The decision is particularly disappointing as experts believe alternative solutions to the problem are available”, they said. 

Fallout 

Noting that the water may contain quantities of radioactive carbon-14, as well as other radioactive isotopes, the independent experts raised their concerns with the Japanese Government that discharging radioactive water to the Pacific Ocean threatens the health of people and planet.  

Meanwhile, in reply to expert concerns, the Japanese Government has suggested that the treated water stored in the tanks was not contaminated.   

However, the experts upheld that the ALPS water processing technology had failed to completely remove radioactive concentrations in most of the contaminated water stored in tanks at the Fukushima Daiichi plant.  

“A first application ALPS failed to clean the water below regulatory levels and there are no guarantees that a second treatment will succeed”, they said, adding that the technology did not remove radioactive tritium or carbon-14.  

Isotope concerns 

While Japan said that the tritium levels are very low and do not pose a threat to human health, scientists warn that in the water, the isotope organically binds to other molecules, moving up the food chain affecting plants and fish and humans. 

Moreover, they say the radioactive hazards of tritium have been underestimated and could pose risks to humans and the environment for over 100 years.    

“We remind Japan of its international obligations to prevent exposure to hazardous substances, to conduct environmental impact assessments of the risks that the discharge of water may have, to prevent transboundary environmental harms, and to protect the marine environment”, the experts concluded. 

Special Rapporteurs and independent experts are appointed by the Geneva-based UN Human Rights Council to examine and report back on a specific human rights theme or a country situation. The positions are honorary and the experts are not paid for their work.

Alert over shortage of new drugs for ‘world’s most dangerous bacteria’  
Alert over shortage of new drugs for ‘world’s most dangerous bacteria’  

The alert from the World Health Organization (WHO) is delivered in a report showing that none of the 43 antibiotics in development today sufficiently addresses the growing threat posed by 13 priority drug-resistant bacteria

“The persistent failure to develop, manufacture, and distribute effective new antibiotics is further fuelling the impact of antimicrobial resistance and threatens our ability to successfully treat bacterial infections,” said Dr. Hanan Balkhy, WHO Assistant Director General on antimicrobial resistance. 

Those most at risk are young children and those living in poverty, but antibiotic-resistant infections can affect anyone, said WHO partner AMR. 

Youngsters at risk 

According to WHO, three in 10 newborns who develop blood infections die, because the antibiotics that are used to treat sepsis are no longer effective. 

Bacterial pneumonia – another preventable illness which has developed resistance to available drugs – is also a major cause of childhood mortality among under-fives. 

WHO’s annual Antibacterial Pipeline Report, notes that almost all antibiotics available today are variations of those discovered by the 1980s.  

We rely hugely on them in all areas of our lives, from having a tooth out at the dentist, to organ transplants and cancer chemotherapy. 

Unproductive pipeline  

But after reviewing antibiotics that are in the clinical stages of testing, as well as those in development, the report highlighted a “near static pipeline” of production, which WHO’s Haileyesus Getahun likened to the “Achilles heel” of global health security.  

“Opportunities emerging from the COVID-19 pandemic must be seized to bring to the forefront the needs for sustainable investments in research and development of new and effective antibiotics,” said Mr. Getahun, WHO Director of Antimicrobial Resistance Global Coordination.   

“We need a global sustained effort including mechanisms for pooled funding and new and additional investments to meet the magnitude of the antimicrobial threat.”  

Only a few drugs have been given early-stage approval by regulators in recent years “and most of these agents…offer limited clinical benefit over existing treatments, WHO said, with the warning that the “rapid emergence of drug-resistance to these new agents” was a certainty. 

The clinical pipeline and recently approved antibiotics are insufficient to tackle the challenge — WHO

Fractional gains 

This was despite the fact that “some promising products” were in different stages of development, as only a fraction of these will make it to market in a sector hampered by the small return on investment from successful antibiotic products, which has limited the interest of most large pharmaceutical companies.  

“Overall, the clinical pipeline and recently approved antibiotics are insufficient to tackle the challenge of increasing emergence and spread of antimicrobial resistance,” the UN agency concluded. 

Driving research 

To promote investment in antibiotics development, WHO and partner Drugs for Neglected Diseases initiative (DNDi) have set up the Global Antibiotic R&D Partnership (GARDP) to develop innovative treatments.  

The UN health agency has also been working closely with other non-profit funding partners such as the CARB-X to accelerate antibacterial research. 

Another important new WHO-partnered initiative is the AMR Action Fund, that was set up by pharmaceutical companies, philanthropists and the European Investment Bank; its aim is to strengthen and accelerate antibiotic development through pooled funding.  

New global compact aims to drive down diabetes deaths, boost insulin access
New global compact aims to drive down diabetes deaths, boost insulin access

The development comes as risk of early death from diabetes is increasing, underscoring why countries must tackle the disease and bring treatment to all who need it. 

The COVID-19 connection 

“The need to take urgent action on diabetes is clearer than ever”, said Tedros Adhanom Ghebreyesus, the WHO Director-General.  

“The number of people with diabetes has quadrupled in the last 40 years.  It is the only major noncommunicable disease for which the risk of dying early is going up, rather than down. And a high proportion of people who are severely ill in hospital with COVID-19 have diabetes.” 

More than 420 million people worldwide live with diabetes, a group of chronic diseases characterized by elevated blood sugar, which can cause damage to the heart, blood vessels, eyes, kidneys and nerves.  

The most common is type 2 diabetes, which occurs when the body becomes resistant to insulin, the hormone that regulates blood sugar. 

Action on insulin 

The global compact focuses on several priorities.  Among the most urgent is increasing access to diabetes diagnostic tools and medicines, particularly insulin, in low and middle-income countries. 

Roughly half of all adults with type 2 diabetes remain undiagnosed, according to WHO.  Additionally, half of all people with the condition do not get the insulin they need, putting them at risk of irreversible complications such as early death, amputation and sight loss. 

The insulin market is currently dominated by three companies, but a pilot programme for WHO prequalification of the medication, introduced two years ago, could change the situation.  The prequalification process ensures medicines meet global standards for quality, safety and efficacy.   

“Prequalification of insulin produced by more manufacturers could help increase the availability of quality-assured insulin to countries that are currently not meeting demand”, WHO said in a press release.

Meanwhile, discussions are underway with manufacturers of insulin, and other diabetes medicines and diagnostic tools, which could help meet demand at prices that countries can afford. 

WHO / Andrew Esiebo / Panos Pictures

A 54-year-old Nigerian man with Type 2 diabetes had to have his right foot amputated (file photo).

Quantifying costs, meeting targets 

Another key aim of the compact is to set a “global price tag” that quantifies the costs and benefits of meeting new targets for diabetes care.  Governments also will be encouraged to meet their commitments to include diabetes prevention and treatment in primary healthcare and universal health coverage packages. 

Dr Bente Mikkelsen, Director of the Department of Noncommunicable Diseases at WHO, added that the compact seeks to rally key stakeholders, as well as people who live with diabetes, around a common agenda to generate new momentum and create solutions. 

“The ‘all hands on deck’ approach to the COVID-19 response is showing us what can be achieved when different sectors work together to find solutions to an urgent public health problem,” he said. 

Share knowledge, foster collaboration 

The new compact was launched at the Global Diabetes Summit, co-hosted by WHO and the Government of Canada, with the support of the University of Toronto. 

“Canada has a proud history of diabetes research and innovation. From the discovery of insulin in 1921 to one hundred years later, we continue working to support people living with diabetes,” said Patty Hajdu, the country’s Minister of Health.  

“But we cannot take on diabetes alone. We must each share knowledge and foster international collaboration to help people with diabetes live longer, healthier lives — in Canada and around the world.”

WHO and partners urge countries to halt sales of wild mammals at food markets
WHO and partners urge countries to halt sales of wild mammals at food markets

The interim guidance, published on Tuesday, is aimed at reducing public health risks associated with these transactions as most emerging infectious diseases have wildlife origins. 

“Globally, traditional markets play a central role in providing food and livelihoods for large populations. Banning the sale of these animals can protect people’s health – both those working there and those shopping there”, they said in a press release. 

No way to check for viruses 

The temporary guidelines were issued by WHO alongside the World Organization for Animal Health (OIE) and the UN Environment Programme (UNEP).   

They said animals, particularly wild animals, are the source of more than 70 per cent of all emerging infectious diseases in humans, many of which are caused by novel viruses. Wild mammals sold in markets pose particular risk as there is no way to check if they carry dangerous viruses. 

“Traditional markets, where live animals are held, slaughtered and dressed, pose a particular risk for pathogen transmission to workers and customers alike,” the guidance stated.

The partners noted that some of the earliest known cases of COVID-19, which is caused by the novel coronavirus SARS-CoV-2, were linked to a traditional food market in Wuhan, China.  Many of the first people to have the disease were stall owners, market employees or regular visitors. 

“It is likely that the virus that causes COVID-19 originated in wild animals, as it belongs to a group of coronaviruses normally found in bats”, they said.    

“One hypothesis is that the virus was initially transmitted to humans through an intermediary animal host that is, as yet, unknown. Another possibility is that the virus was transmitted directly from a host species of animal to humans.” 

Additional hygiene guidance 

In addition to halting sales of wild animals, the guidelines also call for governments to close markets, or sections of markets, and to re-open them “only on condition that they meet required food safety, hygiene and environmental standards and comply with regulations.” 

Authorities are also urged to improve hygiene and sanitation at traditional food markets to reduce transmission of zoonotic diseases. 

“During this pandemic, additional measures for crowd control and physical distancing, hand washing and sanitizing stations as well as education on respiratory hygiene including on use of face masks should be introduced in market settings to limit the possibility of person-to-person transmission of disease,” they added.

COVID ‘long way from over’ as cases and deaths surge – WHO
COVID ‘long way from over’ as cases and deaths surge – WHO

Although January and February saw six consecutive weeks of plummeting COVID-19 cases, the World Health Organization (WHO) chief said that had gone into reverse, with last week yielding “the fourth-highest number of cases in a single week so far”. 

“We have now seen seven consecutive weeks of increasing cases, and four weeks of increasing deaths”, Tedros Adhanom Ghebreyesus told journalists at a regular media briefing. 

Keep physical distancing 

More than 780 million doses of vaccine have now been administered globally, but several Asian and Middle Eastern countries have seen large increases in infections, he said. 

While acknowledging that vaccines are “vital and powerful” instruments, the WHO chief reiterated that they are not the only tools needed to defeat the coronavirus.  

“Physical distancing works. Masks work. Hand hygiene works. Ventilation works. Surveillance, testing, contact tracing, isolation, supportive quarantine and compassionate care – they all work to stop infections and save lives”, Tedros underscored. 

‘Complacency and inconsistency’ 

While stressing the need for “a consistent, coordinated and comprehensive approach” in battling the virus, he said that “confusion, complacency and inconsistency in public health measures and their application, are driving transmission and costing lives”. 

WHO wants to see societies and economies reopening, and travel and trade resuming, instead it is witnessing intensive care units overflowing and people dying, which Tedros maintained “is totally avoidable”. 

He said proven public health measures and strong systems that have enabled countries to respond rapidly and consistently, illustrate that COVID “can be stopped and contained”, adding that those nations are now able to enjoy sporting events, concerts, restaurants and seeing their family and friends safely. 

Increase vaccine output 

Currently, global manufacturing is insufficient to deliver quick, equitable vaccines and other essential health products, according to the WHO official. 

Early in the pandemic, African countries agreed on a coordinated continental approach, “and now they’re coming together for a coordinated approach to scaling up manufacturing”, he said. 

Tedros stressed the importance of investing in “sustainable and secure domestic manufacturing capacity and national regulatory authorities”, asserted that “what can be done today, should be done today”. 

Noting that WHO and its partners have established a COVAX manufacturing taskforce, to increase supply and build a sustainable vaccine manufacturing platform, he offered the UN agency’s technical assistance in assessing the feasibility of local production and to access technology and know-how. 

Bad choices 

Despite continuing transmissions, some countries are re-opening restaurants, night clubs and indoor markets, with too few people taking precautions. 

Moreover, the UN health chief observed that some young people appear to feel that it doesn’t matter if they get COVID-19. 

“Young, healthy people have died. And we still don’t fully understand the long-term consequences of infection for those who survive”, he reminded, echoing reports of some mild cases that have left long-term symptoms, including fatigue, weakness and anxiety. 

While the pandemic is “a long way from over”, Tedros said there were numerous reasons to be optimistic. 

He pointed to the decline in cases and deaths during the first two months of the year as evidence that the virus and its variants can be stopped. 

“With a concerted effort to apply public health measures alongside equitable vaccination, we could bring this pandemic under control in a matter of months”, he attested. 

However, the WHO chief added that this hinges on the decisions and actions that governments and individuals make every day, spelling out: “The choice is ours”.